Hyperthyroidism and myasthenia gravis may occur successively or simultaneously, Myasthenia gravis can occur at various stages of hyperthyroidism. Both diseases are essentially autoimmune diseases. Just like the two enterprises funded by the same consortium, the source is the same, and there may be a common pathogenesis basis between the two: the cross-immune response of the common immune target organ-eye muscle and the common genetic background.
All newly diagnosed myasthenia gravis patients should be screened for hyperthyroidism. If the two diseases occur at the same time, both should be considered in treatment. Generally speaking, there is no conflict in the treatment of the two diseases. If there is no medical contraindication, glucocorticoid therapy can be applied, thymectomy (for myasthenia gravis) can also be performed, and methimazole and levothyroxine tablets can be taken at the same time (for hyperthyroidism).
Patients with myasthenia gravis complicated with hyperthyroidism should appropriately increase the follow-up times and prolong the follow-up time in order to achieve satisfactory clinical results.
Author: Huashan myopathy group
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