Receptor blockers such drugs, such as bisoprolol and metoprolol, mainly achieve antihypertensive and cardiac protection effects by slowing down heart rate and reducing myocardial oxygen consumption. They are more suitable for young and middle-aged patients with fast heart rate, and are more suitable for patients with coronary heart disease, angina pectoris, myocardial infarction and chronic heart failure.
Commonly used drugs
- Long-acting drugs: Bisoprolol and metoprolol sustained-release tablets, usually once per day. Medium and short-acting drugs: metoprolol ordinary tablets, carvedilol, aroprolol, atenolol, etc.
Common adverse reactions mainly include fatigue, cold limbs, bradycardia, etc.
It should be noted that if bradycardia occurs during taking the medicine and the medicine cannot be stopped suddenly, the heart rate will obviously increase (rebound phenomenon) after stopping the medicine, and the patient will feel flustered. If there is coronary heart disease in the past, sudden withdrawal of drugs will aggravate angina pectoris of coronary heart disease. If there is discomfort, slowly and gradually reduce the drug dose before stopping the drug.
Patients with glucose and lipid metabolism abnormalities such as diabetes and hyperlipidemia generally do not choose receptor blockers first, and highly selective receptor blockers (such as bisoprolol and metoprolol) can be selected when necessary;
Receptor blockers are forbidden in patients with asthma or high atrioventricular block, and should be used with caution in patients with chronic obstructive pulmonary disease and heart rate less than 60 beats/minute.
Responsible Editor: Zhang Jingyuan