Liver and kidney are not good, can I still take hypoglycemic drugs?

Sugar friends often have such worries:

I have chronic hepatitis. It is said that taking medicine hurts the liver. Can I not take hypoglycemic drugs?

Doctor, recently I found out that kidney disease is not good. I heard that metformin hurts kidney, so I dare not eat it again!

Many sugar lovers believe that [drugs are divided into three parts], and fear that hypoglycemic drugs will bring damage to the body, especially sugar lovers who are inherently poor in liver and kidney function, are even more resistant to taking hypoglycemic drugs.

However, should we really say goodbye to oral hypoglycemic drugs in order to avoid liver and kidney function damage?

What if the drug is stopped and the blood sugar control is not good?

Today, Dr. Clove will untie this knot for everyone.

Does the liver and kidney [detoxification] of drugs damage the liver and kidney?

Not normally.

There are many kinds of oral hypoglycemic drugs. After entering the human body, these drugs are absorbed in the gastrointestinal tract and enter the blood to exert their efficacy. After completing the task, they are treated in the kidney or liver and excreted with urine or feces after treatment.

This is a process in which drugs are treated, [detoxified] and [detoxified] by the liver and kidney, which are the [treatment plants] in the body.

In general, hypoglycemic drugs will not cause liver and kidney damage. Moreover, patients with liver and kidney diseases already have standardized use of hypoglycemic drugs will not further aggravate liver and kidney diseases.

The liver and kidney function damage occasionally caused by taking certain drugs can be recovered under the guidance of doctors after reduction or withdrawal of drugs, so there is no need to worry too much.

Can’t hypoglycemic drugs be used if there are liver and kidney diseases?


If there are liver and kidney diseases, but the liver and kidney function is not damaged, hypoglycemic drugs can still be used. In case of liver and kidney function damage, hypoglycemic drugs can also be used continuously by adjusting drugs.

How judged that liver and kidney function was damaged?

We need to take blood tests to confirm.

    For liver function, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, glutamyl transpeptidase, etc. can be checked. For renal function, serum creatinine and glomerular filtration rate can be checked.

Liver and kidney function damage, with hypoglycemic drugs what should pay attention to?

Someone asked:

My liver and kidney function is damaged. Am I also all is forgiven when I take hypoglycemic drugs?


There is liver and kidney function damage, oral hypoglycemic drugs, we need to worry about hypoglycemia.

Many oral hypoglycemic drugs need to be discharged out of the body through liver and kidney [detoxification]. If liver and kidney [bad], the speed of these drugs [detoxification] will slow down, thus accumulating in the body.

These hypoglycemic drugs accumulated in the body before they could [detoxify] still stick to their jobs and conscientiously play the role of hypoglycemic. Coupled with the hypoglycemic effect of oral new drugs, this may lead to increased hypoglycemic effect and hypoglycemia.

Once drug accumulation occurs due to liver and kidney function injury, the more hypoglycemic drugs are taken, the higher the probability of hypoglycemia.

Hypoglycemia can induce or aggravate cardiovascular and cerebrovascular diseases and even lead to coma, which sugar lovers need special attention.

The solution to this problem is to pay attention to monitoring blood sugar. Once hypoglycemia occurs, pay attention to timely treatment.

In addition, it should also be noted that the accumulation of some drugs in the body may also increase the production of lactic acid in the body, which is an acidic substance and can cause acidosis after accumulation. Although it is relatively rare, it can also bring great harm to the body.

Liver and kidney function is damaged, how to choose drugs?

In order to avoid hypoglycemia and lactic acidosis, should we still say goodbye to oral hypoglycemic drugs?

Of course not.

Oral hypoglycemic drugs not only reduce blood sugar, but also have certain cardiovascular protection, weight reduction, islet function recovery and other effects. Do not stop using them easily.

Doctors will consider whether sugar lovers have liver and kidney diseases and how liver and kidney functions are, and choose oral hypoglycemic drugs based on strengths and weaknesses.

    For patients with liver function damage, drugs via kidney [detoxification] can be selected. Or still choose liver [detoxifying] drugs, and cooperate with liver-protecting drugs for treatment, and monitor liver function once a month. For patients with renal function impairment, liver [detoxifying] drugs can be selected; For patients with mild to moderate renal injury, the use of renal [detoxification] drugs can also be reduced, and renal function should be monitored once a month. If liver and kidney function is damaged and to a certain extent, doctors may recommend insulin.

At the same time, we need to remind everyone that attention should be paid to monitoring blood sugar during medication. If hypoglycemia occurs frequently, or nausea and vomiting, loss of appetite, skin yellowing, urine color is very yellow, white eyes turn yellow, or sudden urine volume reduction, body edema, this indicates that liver and kidney injury may be further aggravated, and medical treatment should be carried out as soon as possible.

Therefore, we don’t have to worry about the side effects of drugs. Let’s leave these problems to professional doctors.

For oral hypoglycemic drugs, what we need to do is seven words: use the drugs on time and in quantity. Only in this way can we control blood sugar and repel diabetes.