Many people like to eat grapefruit, which is sweet and sour, juicy, nutritious and delicious when squeezed into fruit juice. But do you know that some people are not suitable for eating grapefruit, such as those who are taking statins to reduce lipid.
Let’s talk about popular science, grapefruit and statins [feud].
How did grapefruit and statins get involved?
Pomelo contains a substance called furanocoumarin, which can slow down the metabolic decomposition of statins in the body.
It can be imagined that the longer the drug exists in the body, the longer the time it takes to play its role will also increase, the effect of lowering cholesterol will increase, and some of the side effects originally possessed will also be enlarged.
Studies have shown that taking one tablet of statins with grapefruit juice is equivalent to taking 12-15 tablets of statins with water.
Think about it, when such a large dose of drugs enters our bodies at once, the probability of rare side effects will be greatly increased, and the drugs for curing diseases will become [poison].
Some patients may think, can you drink grapefruit juice and then take less lipid-lowering drugs?
The answer, of course, is no.
Grapefruit juice can only play a certain auxiliary role, who do not know, drink grapefruit juice can replace a few tablets of medicine, how to achieve accurate control of the amount of medicine required by personal illness. Therefore, we cannot try to rely on drinking grapefruit juice to replace standardized medication.
Can’t eat grapefruit?
Current research has found that:
- Statins that are not suitable for taking with grapefruit juice include [simvastatin] and [Lipitor]. For other statins, please consult a professional pharmacist. One cup of grapefruit juice is enough to cause the above adverse reactions. The effect of grapefruit juice in the body also lasts for a long time. Even if you drink grapefruit juice 24 hours after taking the medicine, the statins in the blood will still be affected and the concentration will remain high. Usually it takes 3-7 days before the effect of grapefruit juice slowly disappears.
Patients taking statins should fast grapefruit during taking drugs.
Do other fruits have any effect on statins?
Some citrus fruits have similar effects, such as lime and orange pomelo. However, the more common tangerines, sweet oranges and lemons do not affect. Patients who are taking drugs should be carefully selected.
Is there a similar reaction to what drugs?
Calcium antagonists such as nifedipine, contraceptives, tranquilizers, etc. cannot be taken together with grapefruit juice. They are all common drugs, and the majority of patients should also pay attention to them!